Ftir Spectroscopic Study on Benign and Cancerous Human Breast Tissues - a Run Chart Analysis
نویسندگان
چکیده
Breast cancer tissues have been analyzed to determine the feasibility of the chemical changes taking place in the biological tissue, which can be identified and categorized into various grades. FTIR spectroscopy can be used for qualitative analysis of cancerous breast tissues because of its sensitivity to the changes in the biomolecules in the tissues. IR spectra was taken for a total number of 43 samples of human breast tissues which were already identified as normal, hyperplasia, fibro adenoma, ductal carcinoma and invasive ductal carcinoma breast tissues. The infrared spectrum was recorded in the frequency range between 400 cm and 1100 cm. Some remarkable spectral differences were observed among normal, hyperplasia, fibro adenoma, ductal carcinoma and invasive ductal carcinoma tissues. The absorption bands were found to be at 538 cm, 853 cm, 935 cm, 1005 cm, 1080 cm were found to be the characteristic peaks which differentiate the benign tissues and cancerous breast tissues. The ratios A538/853, A538/935, A538/1005, A538/1080, A853/935 A853/1005, A853/1080, A935/1005, A935/1080, A1005/1080 were also determined and discussed. Thus it implies that FTIR spectroscopy is useful for the qualitative investigation of cancerous breast tissues.
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